Disability in Ohio : Long-Term Care Providers & Programs

This report describes the range of options used in the long-term care system in Ohio. For each provider or program, we report the eligibility requirements, consumer characteristics, capacity, utilization rate, average monthly cost of care, and major payers for services. The programs and providers include Medicaid waiver programs, nursing facilities, adult day service providers, residential care or assisted living facilities, intermediate care facilities for persons with mental retardation, and home- and community-based providers

PASSPORT assessment and services

This report examines the PASSPORT assessment and services processes through thirty case studies: ten new assessments; ten ongoing consumers; and ten disenrolled consumers. We used a combination of observation; interviews with consumers, family caregivers, assessors, and case managers; consumer records review; and one focus group of PASSPORT Administrative site directors or their designees. We evaluated the accuracy and comprehensiveness of assessments; the appropriateness of service plans; and the extent to which consumers and their family members made informed decisions about their care and services

Ohio Long-Term Services and Supports Factbook

This factbook provides a broad overview of Ohio's system of long-term Services and supports. Numerous charts provide descriptions of those who use services, kinds of services, payment systems and other topics. It is designed to be a reference and resource guide

The Ohio Long-Term Care Factbook

This publication describes the current state of long-term care in Ohio as well as projections of the state s future disability rates and LTC needs. It includes descriptions of the variety of settings in which LTC is provided (home and community-based as well as institutional), profiles of LTC residents, sources of LTC funding, and the types of services and forms of caregiving (both formal and informal) that occur in Ohio. A listing of further resources, including websites offering additional information is featured in this fact book

Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine

Despite rapid technical progress and demonstrable effectiveness for some types of diagnosis and therapy, much remains to be learned about clinical genome and exome sequencing (CGES) and its role within the practice of medicine. The Clinical Sequencing Exploratory Research (CSER) consortium includes 18 extramural research projects, one National Human Genome Research Institute (NHGRI) intramural project, and a coordinating center funded by the NHGRI and National Cancer Institute. The consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has thus far recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing. The CSER consortium is analyzing data and creating publically available procedures and tools related to participant preferences and consent, variant classification, disclosure and management of primary and secondary findings, health outcomes, and integration with electronic health records. Future research directions will refine measures of clinical utility of CGES in both germline and somatic testing, evaluate the use of CGES for screening in healthy individuals, explore the penetrance of pathogenic variants through extensive phenotyping, reduce discordances in public databases of genes and variants, examine social and ethnic disparities in the provision of genomics services, explore regulatory issues, and estimate the value and downstream costs of sequencing. The CSER consortium has established a shared community of research sites by using diverse approaches to pursue the evidence-based development of best practices in genomic medicine

Training Case Managers to Administer the Service Adequacy and Satisfaction Instrument (SASI)

This manual provides training for case managers to conduct satisfaction interviews using the Service Adequacy and Satisfaction Instrument. The SASI examines consumer satisfaction with homemaker, personal care, and home-delivered meals services

Training Case Managers to Administer the Service Adequacy and Satisfaction Instrument (SASI)

This manual provides instruction for face-to-face interviewing using the Service Adequacy and Satisfaction Instrument

Exploitation of a “hockey-puck” phenotype to identify pilus and biofilm regulators in Serratia marcescens through genetic analysis

Pili are essential adhesive determinants for many bacterial pathogens. A suppressor mutation screen that takes advantage of a pilus-mediated self-aggregative “hockey-puck” colony phenotype was designed in order to identify novel regulators of type 1 pili in Serratia marcescens. Mutations that decreased pilus biosynthesis mapped to the fimABCD operon, alaT, fkpA, and oxyR, homologs, upstream of the flagellar master regulator operon flhDC, and to an uncharacterized gene encoding a predicted DUF1401 domain. Biofilm formation and pilus-dependent agglutination assays were used to characterize the relative importance of the identified genes in pilus biosynthesis. Additional mutagenic or complementation analysis was used to verify the role of candidate genes in pilus biosynthesis. Presented data support a model that CRP negatively regulates pilus biosynthesis through increased expression of flhDC and decreased expression of oxyR. Further studies are warranted to determine the mechanism by which these genes mediate pilus biosynthesis or function.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author